Asthma Clinical Trials (Spring 2009)
Protocol Name: The Study of Acid Reflux in Children with Asthma
Sponsor: ALA- ACRC / NIH
PI: John Mastronarde, MD / Jonathan Parsons, MD
Coordinator: David Cosmar
Synopsis: Study to determine if treating adolescent asthmatics with Prevacid improves asthma control.
Protocol Name: The Asthma Registry for Contact and Possible Participation in a Future Asthma Research Study
Sponsor: Pulmonary Division/ OSU Asthma Center
PI: John Mastronarde, MD / Jonathan Parsons, MD
Coordinator: David Cosmar
Synopsis: Asthma registry for patients diagnosed with asthma who may be eligible for future studies.
Protocol Name: Mechanisms of exercise induced bronchospasm
Sponsor: OSU Asthma Center/NIH
PI:
Coordinator: David Cosmar
Synopsis: Comparing markers of inflammation in asthmatic participants with and without EIB at baseline and after bronchoprovocation with eucapnic voluntary hyperventilation testing (EVH).
Protocol Name: Micro RNA signatures in acute asthma exacerbations
Sponsor: Pulmonary Division/OSU Asthma Center
PI: Clay Marsh, MD; John Mastronarde, MD ; Melissa Hunter, PhD
Coordinator: David Cosmar
Synopsis: This is a non-randomized, cohort study of the patterns of microvesicles in the serum of participants with atopic and non-atopic asthma.
Protocol Name: Exercise-induced Bronchospasm in Cystic Fibrosis
Sponsor: Pulmonary Division/
PI: John Mastronarde, MD; Stephen Kirkby, MD; Karen McCoy, MD
Coordinator: David Cosmar
Synopsis: This study is designed to determine how often exercise-induced bronchospam occurs in patients with cystic fibrosis.
Protocol Name: Prevalence of exercise-induced asthma in select cohorts of college athletes
Sponsor: Pulmonary Division/
PI:
Coordinator: David Cosmar
Synopsis: This study is investigating how commonly exercise-induced asthma happens in athletes and the best way to diagnose exercise-induced asthma
Protocol: Methacholine Bronchopravocation – Influence of High Potency corticosteroids in Asthma Study (MeCIS)
Sponsor: ALA- ACRC / NIH
PI: John Mastronarde, MD
Coordinator: David Cosmar
Synopsis: This study is being done to see if this methacholine challenge test is a good way of finding out if someone has asthma.
Protocol: Inflammatory Mediators and microRNA Analysis in Premenstrual Asthma
Sponsor: National Institute of Health (NIH)
PI: Jennifer McCallister, MD
Coordinator: David Cosmar
Synopsis: This study is being done to investigate the possible causes of this premenstrual increase in asthma symptoms and to help asthma care providers identify those patients who may suffer from this condition.